SBML model for Pseudomonas-aeruginosa-PAO1
Citations
D. Segre, J. Zucker, J. Katz, X. Lin, P. D'haeseleer, W. Rindone, P. Kharchenko, D. Nguyen, M. Wright, G. Church
"From annotated genomes to metabolic flux models and kinetic parameter fitting,"
OMICS 7:3 301-317 2003
P. Karp, S. Paley, and P. Romero
"The Pathway Tools Software,"
Bioinformatics 18:S225-32 2002
Description
The PSEUDO model was generated from the Organism-specific Pathway/Genome database
Reaction Reaction Equation
EC# 3.6.1.34H<SUP>+</SUP><sub>[cytoplasm]</sub> + H<SUB>2</SUB>O + ATP =H<SUP>+</SUP><sub>[periplasm]</sub> + phosphate + ADP
XMPXAN-RXNxanthosine-5-phosphate + H<SUB>2</SUB>O = xanthosine + phosphate
2-AMINOMUCONATE-REDUCTASE-RXN2-amino-muconate + 2 H<SUB>2</SUB>O + NADH = NH(4)OH + 2-keto-adipate + NAD
XANTHOSINEPHOSPHORY-RXNxanthosine + phosphate = ribose-1-phosphate + xanthine
2-KETO-ADIPATE-DEHYDROG-RXN2-keto-adipate + NAD + Coenzyme A = CO<SUB>2</SUB> + NADH + glutaryl-CoA
UPPSYN-RXN<i>cis,trans</i>-polyisoprenyl<sub>n</sub>-PP + &Delta;<SUP>3</SUP>-isopentenyl-PP = pyrophosphate + <i>cis,trans</i>-polyisoprenyl<sub>n+1</sub>-PP
2-OCTAPRENYL-6-OHPHENOL-METHY-RXN2-octaprenyl-6-hydroxyphenol + S-adenosyl-L-methionine = 2-octaprenyl-6-methoxyphenol + S-adenosyl-homocysteine
UDPACYLGLCNACDEACETYL-RXNUDP-3-O-(3-hydroxymyristoyl)-N-acetylglucosamine + H<SUB>2</SUB>O = UDP-3-O-(3-hydroxymyristoyl)glucosamine + acetate
2-OCTAPRENYL-METHOXY-BENZOQ-METH-RXN2-octaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-homocysteine
THIOREDOXIN-RXNReduced Thioredoxin = Oxidized Thioredoxin + 2 e<SUP>-</SUP>
2-OCTAPRENYLPHENOL-HYDROX-RXN2 2-octaprenylphenol + O<SUB>2</SUB> = 2 2-octaprenyl-6-hydroxyphenol
THIAZOLSYN2-RXNdeoxyxylulose-5-phosphate + ThiS-COSH + L-tyrosine = 4-methyl-5-(&beta;-hydroxyethyl)thiazole phosphate + 4-hydroxy-benzyl-alcohol + C1 of tyrosine + ThiS
2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN2-keto-4-methyl-pentanoate + Coenzyme A + NAD = isovaleryl-CoA + CO<SUB>2</SUB> + NADH
SUCCARGDIHYDRO-RXNN2-Succinyl-L-arginine + 2 H<SUB>2</SUB>O = N<SUP>2</SUP>-succinylornithine + 2 NH<SUB>3</SUB> + CO<SUB>2</SUB>
alpha-ketoglutarate oxidative decarboxylation2-oxoglutarate + Coenzyme A + NAD = succinyl-CoA + CO<SUB>2</SUB> + NADH + H<SUP>+</SUP>
2TRANSKETO-RXNerythrose-4-phosphate + xylulose-5-phosphate = fructose-6-phosphate + glyceraldehyde-3-phosphate
RXNB-3533-ketoadipyl-CoA + Coenzyme A = acetyl-CoA + succinyl-CoA
3-HYDROXY-KYNURENINASE-RXN3-hydroxy-L-kynurenine + H<SUB>2</SUB>O = 3-hydroxy-anthranilate + L-alanine
RXN0-748GDP + Grx = dGDP + GrxA + H<SUB>2</SUB>O
3-OXOACYL-ACP-COA-SYNTHIII-RXNacetyl-CoA + malonyl-ACP = acetoacetyl-ACP + Coenzyme A + CO<SUB>2</SUB>
RXN0-747ADP + Grx = dADP + GrxA + H<SUB>2</SUB>O
3.1.1.--RXN1,2-diacylglycerol + H<SUB>2</SUB>O = Acylglycerol + a fatty acid
RXN0-746GTP + reduced flavodoxin = deoxy-GTP + oxidized flavodoxin + H<SUB>2</SUB>O
RXN0-745ATP + reduced flavodoxin = deoxy-ATP + oxidized flavodoxin + H<SUB>2</SUB>O
ACETYLSYNCLTH-RXNcarbon monoxide + [Co-E-CH<SUB>3</SUB>] + Coenzyme A = acetyl-CoA + [Co-E]
RXN0-743N<sup>5</sup>-carboxyaminoimidazole ribonucleotide = phosphoribosyl-carboxy-aminoimidazole
ACONITATEHYDR-RXNcis-aconitate + H<SUB>2</SUB>O = isocitrate
RXN0-7425'-phosphoribosyl-5-aminoimidazole + ATP + H<SUB>2</SUB>O + CO<SUB>2</SUB> = N<sup>5</sup>-carboxyaminoimidazole ribonucleotide + ADP + phosphate
ADDALT-RXNNH<SUB>3</SUB> + deoxyinosine = H<SUB>2</SUB>O + deoxyadenosine
RXN0-724UTP + reduced flavodoxin = dUTP + oxidized flavodoxin + H<SUB>2</SUB>O
RXN0-723CTP + reduced flavodoxin = dCTP + oxidized flavodoxin + H<SUB>2</SUB>O
EC# 2.4.2.-ribose-1-phosphate + adenine = adenosine + phosphate
RXN0-306arsenate + reduced glutathione = arsenite + oxidized glutathione
ADOMET-DMK-METHYLTRANSFER-RXNdemethylmenaquinone + S-adenosyl-L-methionine = menaquinone + S-adenosyl-homocysteine
RXN0-3024-diphosphocytidyl-2-C-methylerythritol 2-phosphate = 2-C-methyl-D-erythritol-2,4-cyclodiphosphate + CMP
EC# 1.1.1.-acetaldehyde + NADH = ethanol + NAD
RXN0-2772-C-methyl-D-erythritol-4-phosphate + CTP = 4-diphosphocytidyl-2-C-methylerythritol + pyrophosphate
ALLYSINE-DEHYDROG-RXNH<SUB>2</SUB>O + allysine + NAD = L-2-Aminoadipate + NADH
RXN0-262molybdopterin + GTP = molybdopterin guanine dinucleotide + pyrophosphate
AMINO-CARBOXYMUCONATE-SEMIALDEHYDE-RXN2-amino-3-carboxymuconate semialdehyde = CO<SUB>2</SUB> + 2-aminomuconate semialdehyde
EC# 1.8.1.-PAPS + NADPH = SO<SUB>3</SUB> + adenosine 3',5'-bisphosphate + NADP
EC# 1.1.1.-3-hydroxybutyryl-CoA + NAD = acetoacetyl-CoA + NADH
RIBOPHOSPHAT-RXN5-amino-2,6-dioxy-4-(5'-phosphoribitylamino)pyrimidine + H<SUB>2</SUB>O = 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione + phosphate
EC# 2.-.-.-adenosylcobinamide-GDP + &alpha;-ribazole = adenosylcobalamin + GMP
EC# 1.17.4.-CDP + Grx = dCDP + GrxA + H<SUB>2</SUB>O
COBINAMIDEKIN-RXNadenosylcobinamide + ATP = adenosylcobinamide-P + ADP
RIBOFLAVINSYNREDUC-RXNNADPH + H<SUP>+</SUP> + 5-amino-6-(ribosylamino)-2,4-(1H,3H)-pyrimidinedione 5'-phosphate = NADP + 5-amino-2,6-dioxy-4-(5'-phosphoribitylamino)pyrimidine
COBINPGUANYLYLTRANS-RXNadenosylcobinamide-P + GTP = adenosylcobinamide-GDP + pyrophosphate
RIBOFLAVINSYNDEAM-RXNH<SUB>2</SUB>O + 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine = NH<SUB>3</SUB> + 5-amino-6-(ribosylamino)-2,4-(1H,3H)-pyrimidinedione 5'-phosphate
EC# 2.7.1.-cytidine + GTP = CMP + GDP
EC# 2.7.-.-adenosylcobinamide + ATP = adenosylcobinamide-P + ADP
CYTOCHROME-B-RXNcytochrome b oxidized + 2 e<SUP>-</SUP> = reduced cytochrome b
R346-RXN1-amino-propan-2-ol + adenosyl-cobyric acid = adenosylcobinamide
DEOXYADENPHOSPHOR-RXNdeoxyadenosine + phosphate = adenine + deoxy-ribose-1-phosphate
EC# 1.-.-.-cob(II)yrinic acid a,c-diamide + NADH = cob(I)yrinic acid a,c-diamide + NAD
DEOXYGUANPHOSPHOR-RXNguanine + deoxy-ribose-1-phosphate = deoxyguanosine + phosphate
R342-RXNhydrogenobyrinate a,c-diamide + Co<SUP>2+</SUP> + ATP = cob(II)yrinic acid a,c-diamide + ADP + phosphate
DEOXYINOPHOSPHOR-RXNhypoxanthine + deoxy-ribose-1-phosphate = deoxyinosine + phosphate
EC# 1.-.-.-precorrin-3A = precorrin-3B
DIMETHUROPORDEHYDROG-RXNdihydrosirohydrochlorin + NAD = sirohydrochlorin + NADH
EC# 2.7.-.-4-diphosphocytidyl-2-C-methylerythritol + ATP = 4-diphosphocytidyl-2-C-methylerythritol 2-phosphate + ADP
DIOHBUTANONEPSYN-RXNribulose-5-phosphate = 3,4-dihydroxy-2-butanone-4-P + formate
QUINOLINATE-SYNTHA-RXNiminoaspartate + dihydroxy-acetone-phosphate = quinolinate + 2 H<SUB>2</SUB>O + phosphate
DISULFOXRED-RXNa protein with reduced SH groups + protein with reduced SH groups = a protein with oxidized disulfide bonds + protein with oxidized disulfide bonds
PYRUVDEH-RXNpyruvate + Coenzyme A + NAD = acetyl-CoA + CO<SUB>2</SUB> + NADH + H<SUP>+</SUP>
EC# 5.-.-.-GDP-4-dehydro-6-deoxy-D-mannose = GDP-4-dehydro-6-L-deoxygalactose
PYRPBIOPRO-PDXJ-A-RXNphospho-hydroxy-threonine + deoxyxylulose-5-phosphate = pyridoxine-5'-phosphate + CO<SUB>2</SUB>
EC# 1.-.-.-GDP-4-dehydro-6-L-deoxygalactose + NADPH + H<SUP>+</SUP> = guanosine diphosphate fucose + NADP
PYRIMSYN1-RXN5'-phosphoribosyl-5-aminoimidazole = 4-amino-5-hydroxymethyl-2-methylpyrimidine-phosphate
FORMYLTHFGLUSYNTH-RXN10-formyl-THF(glu)<sub>n</sub> + L-glutamate + ATP = 10-formyl-THF(glu)<sub>n+1</sub> + ADP + phosphate
PYRAMKIN-RXNATP + pyridoxamine = ADP + pyridoxamine 5'-phosphate
GCVMULTI-RXNL-glycine + THF + NAD = NH<SUB>3</SUB> + CO<SUB>2</SUB> + 5,10-methylene-THF + NADH + H<SUP>+</SUP>
PUTTRANSAM-RXNputrescine + 2-oxoglutarate = 4-amino-butyraldehyde + L-glutamate
GDPMANMANHYDRO-RXNGDP-mannose + H<SUB>2</SUB>O = GDP + mannose
PNPOXI-RXNO<SUB>2</SUB> + pyridoxine-5'-phosphate = H<SUB>2</SUB>O<SUB>2</SUB> + pyridoxal 5'-phosphate
GDPPYPHOSKIN-RXNATP + GDP = AMP + guanosine 5'-diphosphate,3'-diphosphate
PHOSNACMURPENTATRANS-RXNundecaprenyl phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate- D-alanyl-D-alanine = N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptane- D-alanyl-D-alanine-diphosphoundecaprenol + UMP
GLUCOSAMINE1PACETYL-RXNglucosamine-1P + acetyl-CoA = N-acetyl-glucosamine-1-phosphate + Coenzyme A
PHOSGLUCOSAMINEMUT-RXND-glucosamine-6-phosphate = glucosamine-1P
GLUTAREDOXIN-RXNGrxA + 2 e<SUP>-</SUP> = Grx
PDXJ-RXN1-amino-propan-2-one-3-phosphate + deoxyxylulose-5-phosphate = pyridoxine-5'-phosphate
GLUTARYL-COA-DEHYDROG-RXNglutaryl-CoA + FAD = glutaconyl-CoA + FADH<SUB>2</SUB>
PDXA-RXNphospho-hydroxy-threonine + NAD = 1-amino-propan-2-one-3-phosphate + NADH + CO<SUB>2</SUB>
GLYCOPHOSPHORYL-RXNGlycogens + phosphate = maltodextrin + glucose-1-phosphate
OCTAPRENYL-METHYL-METHOXY-BENZOQ-OH-RXN2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + O<SUB>2</SUB> = 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone
GLYMALTOPHOSPHORYL-RXNGlycogens + phosphate = maltotetraose + glucose-1-phosphate
METLENETHFRED-FERRE-RXN5,10-methylene-THF + FdxA = 5-methyl-THF + oxidized ferredoxin
GUANOSINEKIN-RXNguanosine + ATP = GMP + ADP
MALTET-RXNmaltotetraose + H<SUB>2</SUB>O = maltotriose + &beta;-D-glucose
EC# 2.4.2.-guanine + PRPP = pyrophosphate + GMP
MALONYL-ACPDECARBOX-RXNmalonyl-ACP = acetyl-ACP + CO<SUB>2</SUB>
MALDEXPHOSPHORYL-RXNmaltodextrin + phosphate = maltotetraose + glucose-1-phosphate
HYPXPRIBOSYLTRAN-RXNhypoxanthine + PRPP = pyrophosphate + IMP
LUMAZINESYN-RXN3,4-dihydroxy-2-butanone-4-P + 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione = 6,7-dimethyl-8-(1-D-ribityl)lumazine + phosphate
EC# 2.4.2.-inosine + phosphate = ribose-1-phosphate + hypoxanthine
LIPIDXSYNTHESIS-RXNH<SUB>2</SUB>O + UDP-2,3-bis(3-hydroxymyristoyl)glucosamine = 2,3-bis(3-hydroxymyristoyl)-&beta;-D-glucosaminyl 1-phosphate + UMP
lactate oxidationFMN + lactate = FMNH<SUB>2</SUB> + pyruvate
EC# 2.7.7.56a tRNA + phosphate + TRNA(N+1) = a ribonucleoside diphosphate + a tRNA + A NUCLEOSIDE DIPHOSPHATE + TRNA(N)
EC# 2.4.2.29QUEUOSINE + TRNA GUANINE = guanine + TRNA QUEUOSINE
EC# 2.5.1.8a tRNA + TRNA + &Delta;<SUP>3</SUP>-isopentenyl-PP = TRNA CONTAINING 6-ISOPENTENYLADENOSINE + pyrophosphate
EC# 2.1.1.31a tRNA + TRNA + S-adenosyl-L-methionine = TRNA CONTAINING N1-METHYLGUANINE + S-adenosyl-homocysteine
EC# 2.1.1.35a tRNA + TRNA + S-adenosyl-L-methionine = a tRNA containing thymine + TRNA CONTAINING THYMINE + S-adenosyl-homocysteine
EC# 6.1.1.9tRNA<SUP>val</SUP> + L-valine + ATP = L-valyl-tRNA<SUP>val</SUP> + pyrophosphate + AMP
EC# 6.1.1.7tRNA<SUP>ala</SUP> + L-alanine + ATP = L-alanyl-tRNA<SUP>ala</SUP> + pyrophosphate + AMP
EC# 6.1.1.1tRNA<SUP>tyr</SUP> + L-tyrosine + ATP = L-tyrosyl-tRNA<SUP>tyr</SUP> + pyrophosphate + AMP
EC# 6.1.1.19tRNA<SUP>arg</SUP> + L-arginine + ATP = L-arginyl-tRNA<SUP>arg</SUP> + pyrophosphate + AMP
EC# 6.1.1.2tRNA<SUP>trp</SUP> + L-tryptophan + ATP = L-tryptophanyl-tRNA<SUP>trp</SUP> + pyrophosphate + AMP
EC# 6.1.1.22tRNA<SUP>asn</SUP> + L-asparagine + ATP = L-asparaginyl-tRNA<SUP>asn</SUP> + pyrophosphate + AMP
EC# 6.1.1.3tRNA<SUP>thr</SUP> + L-threonine + ATP = L-threonyl-tRNA<SUP>thr</SUP> + pyrophosphate + AMP
EC# 6.1.1.12tRNA<SUP>asp</SUP> + L-aspartate + ATP = L-aspartyl-tRNA<SUP>asp</SUP> + pyrophosphate + AMP
EC# 6.1.1.11tRNA<SUP>ser</SUP> + L-serine + ATP = L-seryl-tRNA<SUP>ser</SUP> + pyrophosphate + AMP
EC# 6.1.1.16tRNA<SUP>cys</SUP> + L-cysteine + ATP = L-cysteinyl-tRNA<SUP>cys</SUP> + pyrophosphate + AMP
EC# 6.1.1.15tRNA<SUP>pro</SUP> + L-proline + ATP = L-prolyl-tRNA<SUP>pro</SUP> + pyrophosphate + AMP
EC# 6.1.1.20tRNA<SUP>phe</SUP> + L-phenylalanine + ATP = L-phenylalanyl-tRNA<SUP>phe</SUP> + pyrophosphate + AMP
EC# 6.1.1.18tRNA<SUP>gln</SUP> + L-glutamine + ATP = L-glutaminyl-tRNA<SUP>gln</SUP> + pyrophosphate + AMP
EC# 6.1.1.10tRNA<SUP>met</SUP> + L-methionine + ATP = L-methionyl-tRNA<SUP>met</SUP> + pyrophosphate + AMP
EC# 6.1.1.14tRNA<SUP>gly</SUP> + L-glycine + ATP = glycyl-tRNA<SUP>gly</SUP> + pyrophosphate + AMP
EC# 6.1.1.6tRNA<SUP>lys</SUP> + L-lysine + ATP = L-lysyl-tRNA<SUP>lys</SUP> + pyrophosphate + AMP
EC# 6.1.1.21tRNA<SUP>his</SUP> + L-histidine + ATP = L-histidyl-tRNA<SUP>his</SUP> + pyrophosphate + AMP
EC# 6.1.1.4tRNA<SUP>leu</SUP> + L-leucine + ATP = L-leucyl-tRNA<SUP>leu</SUP> + pyrophosphate + AMP
EC# 6.1.1.5tRNA<SUP>ile</SUP> + L-iso-leucine + ATP = L-isoleucyl-tRNA<SUP>ile</SUP> + pyrophosphate + AMP
EC# 5.4.99.12TRNA URIDINE = TRNA PSEUDOURIDINE
EC# 1.-.-.-coproporphyrinogen III + NAD(P)(+) = protoporphyrinogen + NAD(P)H
EC# 1.-.-.-L-glutamyl-tRNA<SUP>glt</SUP> + NADPH = glutamate-1-semialdehyde + NADP + tRNA<SUP>glt</SUP>
EC# 1.1.-.-an alkanesulfonate + an alkanesulfonate + O<SUB>2</SUB> + FMNH<SUB>2</SUB> = an aldehyde + SO<SUB>3</SUB> + H<SUB>2</SUB>O + FMN
EC# 1.1.1.204H<SUB>2</SUB>O + NAD + xanthine = NADH + urate
EC# 1.1.1.76NAD + (S,S)-Butane-2,3-diol = NADH + acetoin
EC# 1.1.1.22H<SUB>2</SUB>O + 2 NAD + UDP-D-glucose = 2 NADH + UDP-D-glucuronate
EC# 1.1.1.43NADPH + 6-Phospho-2-dehydro-D-gluconate = NADP + 6-phospho-gluconate
EC# 1.1.1.158NADPH + UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine = NADP + UDP-N-acetylmuramate
EC# 1.1.1.1692-dehydropantoate + NADPH = L-pantoate + NADP
EC# 1.1.1.60NADPH + tartronate semialdehyde = NADP + glycerate
EC# 1.1.1.30NAD + (R)-3-Hydroxybutanoate = NADH + acetoacetate
EC# 1.1.1.140D-sorbitol 6-phosphate + NAD = fructose-6-phosphate + NADH
EC# 1.1.1.31NAD + 3-hydroxy-isobutyrate = NADH + methylmalonate-semialdehyde
EC# 1.1.1.25NADPH + 3-dehydro-shikimate = NADP + shikimate
EC# 1.1.1.852-D-threo-hydroxy-3-carboxy-isocaproate + NAD = 2-keto-4-methyl-pentanoate + NADH + H<SUP>+</SUP> + CO<SUB>2</SUB>
EC# 1.1.1.-glucose-6-phosphate + NAD = 6-phospho-gluconate + NADH + H<SUP>+</SUP>
EC# 1.1.1.100NADPH + H<SUP>+</SUP> + &beta;-ketoacyl-ACP = D-3-hydroxy-acyl-ACP + NADP
EC# 1.1.1.-oxalosuccinate = 2-oxoglutarate + CO<SUB>2</SUB>
EC# 1.1.1.446-phospho-gluconate + NADP = NADPH + H<SUP>+</SUP> + CO<SUB>2</SUB> + ribulose-5-phosphate
EC# 1.1.1.-isocitrate + NAD(P)(+) = oxalosuccinate + NAD(P)H + H<SUP>+</SUP>
EC# 1.1.1.862-aceto-2-hydroxy-butyrate + NADPH + H<SUP>+</SUP> = 2,3-dihydroxy-3-methylvalerate + NADP
EC# 1.1.1.154(S)-Ureidoglycolate + NAD(P)(+) = Oxalureate + NAD(P)H
EC# 1.1.1.1NAD + an alcohol = NADH + an aldehyde or ketone
EC# 1.1.1.953-phosphoglycerate + NAD = 3-phospho-hydroxypyruvate + NADH
EC# 1.1.1.28NADH + pyruvate = NAD + D-lactate
EC# 1.1.1.67NAD + mannitol = NADH + fructose
EC# 1.1.1.133NADPH + dTDP-4-dehydro-6-deoxy-L-mannose = NADP + dTDP-rhamnose
EC# 1.1.1.40NADP + malate = NADPH + CO<SUB>2</SUB> + pyruvate
EC# 1.1.1.-deoxyxylulose-5-phosphate + NADPH = 2-C-methyl-D-erythritol-4-phosphate + NADP
EC# 1.1.1.38NAD + malate = NADH + CO<SUB>2</SUB> + pyruvate
EC# 1.1.1.-erythronate-4-phosphate + NAD = 3-hydroxy-4-phospho-hydroxy-&alpha;-ketobutyrate + NADH
EC# 1.1.1.37malate + NAD = oxaloacetic acid + NADH + H<SUP>+</SUP>
EC# 1.1.1.187NADPH + GDP-4-dehydro-6-deoxy-D-mannose = NADP + GDP-6-deoxy-D-mannose
EC# 1.1.1.27NAD + lactate = NADH + pyruvate
EC# 1.1.1.132H<SUB>2</SUB>O + 2 NAD + GDP-mannose = 2 NADH + GDP-mannuronate
EC# 1.1.1.42isocitrate + NADP = NADPH + H<SUP>+</SUP> + 2-oxoglutarate + CO<SUB>2</SUB>
EC# 1.1.1.49glucose-6-phosphate + NADP = D-6-phospho-glucono-&delta;-lactone + NADPH + H<SUP>+</SUP>
EC# 1.1.1.205H<SUB>2</SUB>O + NAD + IMP = xanthosine-5-phosphate + NADH
EC# 1.1.1.69NAD(P)H + 5-ketogluconate = NAD(P)(+) + gluconate
EC# 1.1.1.-L-idonate + NAD = NADH + 5-ketogluconate
EC# 1.1.1.94NAD(P)(+) + glycerol-3-phosphate = NAD(P)H + H<SUP>+</SUP> + dihydroxy-acetone-phosphate
EC# 1.1.1.81NAD(P)H + hydroxypyruvate = glycerate + NAD(P)(+)
EC# 1.1.1.6NAD + glycerol = NADH + dihydroxy-acetone
EC# 1.1.1.3NADPH + H<SUP>+</SUP> + L-aspartate-semialdehyde = NADP + homoserine
EC# 1.1.1.29NAD + glycerate = NADH + hydroxypyruvate
EC# 1.1.1.23histidinol + NAD = histidinal + NADH + H<SUP>+</SUP>
EC# 1.1.1.23histidinal + NAD + H<SUB>2</SUB>O = L-histidine + NADH + H<SUP>+</SUP>
EC# 1.1.99.-octanol + acceptor = 1-Octanal + reduced acceptor
EC# 1.1.99.-(S)-4-Hydroxymandelate + acceptor = 4-Hydroxybenzoylformate + reduced acceptor
EC# 1.1.99.16acceptor + malate = reduced acceptor + oxaloacetic acid
EC# 1.1.99.1choline + acceptor = betaine aldehyde + reduced acceptor
EC# 1.1.99.5acceptor + glycerol-3-phosphate = reduced acceptor + dihydroxy-acetone-phosphate
EC# 1.1.99.17&beta;-D-glucose + NADP = glucono-&delta;-lactone + NADPH + H<SUP>+</SUP>
EC# 1.1.99.5FAD + glycerol-3-phosphate = FADH<SUB>2</SUB> + dihydroxy-acetone-phosphate
EC# 1.1.3.15O<SUB>2</SUB> + (S)-2-HYDROXY-ACID = H<SUB>2</SUB>O<SUB>2</SUB> + 2-OXO ACID
EC# 1.10.2.-ubiquinol(40) + O<SUB>2</SUB> = ubiquinone(40) + H<SUB>2</SUB>O
EC# 1.11.1.7reduced acceptor + H<SUB>2</SUB>O<SUB>2</SUB> = acceptor + H<SUB>2</SUB>O
EC# 1.11.1.62 H<SUB>2</SUB>O<SUB>2</SUB> = 2 H<SUB>2</SUB>O + O<SUB>2</SUB>
EC# 1.11.1.9H<SUB>2</SUB>O<SUB>2</SUB> + 2 reduced glutathione = oxidized glutathione + 2 H<SUB>2</SUB>O
EC# 1.11.1.10Cl + 2 H<SUB>2</SUB>O<SUB>2</SUB> + 2 RH = 2 H<SUB>2</SUB>O + 2 RCL
EC# 1.9.3.1O<SUB>2</SUB> + 4 FERROCYTOCHROME C = 2 H<SUB>2</SUB>O + 4 FERRICYTOCHROME C
EC# 1.8.99.1H<SUB>2</SUB>O + acceptor + H<SUB>2</SUB>S = reduced acceptor + SO<SUB>3</SUB>
EC# 1.8.1.23 NADPH + SO<SUB>3</SUB> = 3 H<SUB>2</SUB>O + 3 NADP + H<SUB>2</SUB>S
EC# 1.8.1.4dihydrolipoamide + NAD = lipoamide + NADH + H<SUP>+</SUP>
EC# 1.8.4.6a protein L-methionine + Oxidized Thioredoxin + PROTEIN L-METHIONINE = a protein L-methionine S-oxide + Reduced Thioredoxin + PROTEIN L-METHIONINE S-OXIDE
EC# 1.8.4.22 reduced glutathione + GrxA = oxidized glutathione + Grx
EC# 1.13.11.11O<SUB>2</SUB> + L-tryptophan = L-Formylkynurenine
EC# 1.13.11.15O<SUB>2</SUB> + 3,4-Dihydroxyphenylacetate = 2-Hydroxy-5-carboxymethylmuconate semialdehyde
EC# 1.13.11.3Gallate + O<SUB>2</SUB> = 2-Pyrone-4,6-dicarboxylate + H<SUB>2</SUB>O
EC# 1.13.11.6O<SUB>2</SUB> + 3-hydroxy-anthranilate = 2-amino-3-carboxymuconate semialdehyde
EC# 1.13.11.3O<SUB>2</SUB> + protocatechuate = 3-Carboxy-cis,cis-muconate
EC# 1.13.11.27p-hydroxyphenylpyruvate + O<SUB>2</SUB> = CO<SUB>2</SUB> + homogentisate
EC# 1.13.11.12O<SUB>2</SUB> + linoleic acid = 13(S)-hydroperoxyoctadeca-9,11-dienoate
EC# 1.13.11.1O<SUB>2</SUB> + catechol = cis,cis-muconate
EC# 1.13.11.5O<SUB>2</SUB> + homogentisate = 4-maleyl-acetoacetate
EC# 1.13.11.4O<SUB>2</SUB> + 2,5-Dihydroxybenzoate = Maleylpyruvate
EC# 1.7.99.6reduced acceptor + nitrous oxide = N<sub>2</sub> + acceptor
EC# 1.7.99.5NADH + 5,10-methylene-THF = NAD + 5-methyl-THF
EC# 1.7.99.3acceptor + 2 H<SUB>2</SUB>O + 2 nitric oxide = reduced acceptor + 2 nitrite
EC# 1.7.99.4reduced acceptor + NO<SUB>3</SUB><SUP>-</SUP> = acceptor + nitrite
EC# 1.7.99.7reduced acceptor + nitric oxide = acceptor + nitrous oxide
EC# 1.6.6.1NO<SUB>3</SUB><SUP>-</SUP> + NADH = H<SUB>2</SUB>O + nitrite + NAD
EC# 1.6.6.2NO<SUB>3</SUB><SUP>-</SUP> + NAD(P)H = H<SUB>2</SUB>O + nitrite + NAD(P)(+)
EC# 1.7.7.22 oxidized ferredoxin + H<SUB>2</SUB>O + nitrite = 2 FdxA + NO<SUB>3</SUB><SUP>-</SUP>
EC# 1.7.2.12 FERROCYTOCHROME C + nitrite = 2 FERRICYTOCHROME C + H<SUB>2</SUB>O + nitric oxide
EC# 1.7.3.3H<SUB>2</SUB>O<SUB>2</SUB> + urate = CO<SUB>2</SUB> + allantoin
EC# 1.14.99.5O<SUB>2</SUB> + reduced acceptor + STEAROYL-COA = 2 H<SUB>2</SUB>O + acceptor + OLEOYL-COA
EC# 1.14.-.-taurine + 2-oxoglutarate + O<SUB>2</SUB> = aminoacetaldehyde + SO<SUB>3</SUB> + succinate + CO<SUB>2</SUB>
EC# 1.14.3.-2-octaprenyl-6-methoxyphenol + O<SUB>2</SUB> = 2-octaprenyl-6-methoxy-1,4-benzoquinone + H<SUB>2</SUB>O
EC# 1.14.12.-2 nitric oxide + 2 O<SUB>2</SUB> + NAD(P)H = 2 NO<SUB>3</SUB><SUP>-</SUP> + NAD(P)(+) + H<SUP>+</SUP>
EC# 1.14.13.9O<SUB>2</SUB> + NADPH + kynurenine = H<SUB>2</SUB>O + NADP + 3-hydroxy-L-kynurenine
EC# 1.14.13.3O<SUB>2</SUB> + NADH + 4-hydroxyphenylacetate = H<SUB>2</SUB>O + NAD + 3,4-Dihydroxyphenylacetate
EC# 1.14.13.2O<SUB>2</SUB> + NADPH + p-hydroxybenzoate = H<SUB>2</SUB>O + NADP + protocatechuate
EC# 1.14.13.8O<SUB>2</SUB> + NADPH + N,N-dimethylaniline = H<SUB>2</SUB>O + NADP + N,N-DIMETHYLANILINE N-OXIDE
EC# 1.14.14.1O<SUB>2</SUB> + REDUCED FLAVOPROTEIN + RH = H<SUB>2</SUB>O + OXIDIZED FLAVOPROTEIN + an alcohol
EC# 1.14.15.3O<SUB>2</SUB> + REDUCED RUBREDOXIN + octane = H<SUB>2</SUB>O + OXIDIZED RUBREDOXIN + octanol
EC# 1.14.16.1O<SUB>2</SUB> + tetra-hydro-biopterin + L-phenylalanine = H<SUB>2</SUB>O + biopterin + L-tyrosine
EC# 1.6.99.1acceptor + NADPH = reduced acceptor + NADP
EC# 1.6.99.3acceptor + NADH = reduced acceptor + NAD
EC# 1.6.1.1NAD + NADPH = NADH + NADP
EC# 1.6.1.2NAD + NADPH = NADH + NADP
EC# 1.6.8.1NADPH + FMN = NADP + FMNH<SUB>2</SUB>
EC# 1.6.4.5Oxidized Thioredoxin + NADPH = Reduced Thioredoxin + NADP
EC# 1.6.4.2oxidized glutathione + NADPH = 2 reduced glutathione + NADP
EC# 1.6.4.-an alkylhydroperoxide + ROOH + H<SUP>+</SUP> + NADH = an alcohol + H<SUB>2</SUB>O + NAD
EC# 1.6.5.5NADPH + a quinone = NADP + a semiquinone
EC# 1.6.5.3ubiquinone(40) + NADH + H<SUP>+</SUP> = ubiquinol(40) + NAD
EC# 1.6.5.3ubiquinone(50) + NADH + H<SUP>+</SUP> = Ubiquinols + ubiquinol(50) + NAD
EC# 1.15.1.12 H<SUP>+</SUP> + 2 O<SUB>2</SUB><SUP>-</SUP> = H<SUB>2</SUB>O<SUB>2</SUB> + O<SUB>2</SUB>
EC# 1.5.99.1H<SUB>2</SUB>O + acceptor + sarcosine = reduced acceptor + formaldehyde + L-glycine
EC# 1.5.99.8L-4-hydroxy-proline + FAD = pyrroline-hydroxy-carboxylate + FADH<SUB>2</SUB>
EC# 1.5.99.8L-proline + FAD = L-&Delta;<SUP>1</SUP>-pyrroline-5-carboxylate + FADH<SUB>2</SUB>
EC# 1.5.1.2NADPH + L-&Delta;<SUP>1</SUP>-pyrroline-5-carboxylate = L-proline + NADP
EC# 1.5.1.8NADPH + 2-oxoglutarate + L-lysine = H<SUB>2</SUB>O + NADP + saccharopine
EC# 1.5.1.12L-&Delta;<SUP>1</SUP>-pyrroline-5-carboxylate + NAD + 2 H<SUB>2</SUB>O = L-glutamate + NADH
EC# 1.5.1.9H<SUB>2</SUB>O + NAD + saccharopine = NADH + allysine + L-glutamate
EC# 1.5.1.5NADP + 5,10-methylene-THF = NADPH + 5,10-methenyl-THF
EC# 1.5.1.3NADPH + 7,8-dihydrofolate = NADP + THF
EC# 1.5.1.12pyrroline-hydroxy-carboxylate + NADH + 2 H<SUB>2</SUB>O = L-erythro-4-hydroxy-glutamate + NAD
EC# 1.5.3.1O<SUB>2</SUB> + H<SUB>2</SUB>O + sarcosine = H<SUB>2</SUB>O<SUB>2</SUB> + formaldehyde + L-glycine
EC# 1.5.5.1ubiquinone(50) + ETF reduced = Ubiquinols + ubiquinol(50) + ETF oxidized
EC# 1.4.99.1a D amino acid + acceptor + H<SUB>2</SUB>O + a D-amino acid = a 2-oxo acid + reduced acceptor + NH<SUB>3</SUB> + a 2-oxo acid
EC# 1.4.1.9NAD + H<SUB>2</SUB>O + L-leucine = NADH + NH<SUB>3</SUB> + 2-keto-4-methyl-pentanoate
EC# 1.4.1.13L-glutamine + 2-oxoglutarate + NADPH = 2 L-glutamate + NADP
EC# 1.4.1.4L-glutamate + H<SUB>2</SUB>O + NADP = 2-oxoglutarate + NH<SUB>3</SUB> + NADPH + H<SUP>+</SUP>
EC# 1.4.4.2lipoyl-GcvH-protein + L-glycine = CO<SUB>2</SUB> + S-aminomethyldihydrolipoyl-GcvH-protein
EC# 1.4.3.5O<SUB>2</SUB> + H<SUB>2</SUB>O + pyridoxamine 5'-phosphate = H<SUB>2</SUB>O<SUB>2</SUB> + NH<SUB>3</SUB> + pyridoxal 5'-phosphate
EC# 1.4.3.-L-arginine + O<SUB>2</SUB> + H<SUB>2</SUB>O = 2-Oxoarginine + H<SUB>2</SUB>O<SUB>2</SUB> + NH<SUB>3</SUB>
EC# 1.4.3.16O<SUB>2</SUB> + H<SUB>2</SUB>O + L-aspartate = H<SUB>2</SUB>O<SUB>2</SUB> + NH<SUB>3</SUB> + oxaloacetic acid
EC# 1.4.3.3a D amino acid + O<SUB>2</SUB> + H<SUB>2</SUB>O + A D-AMINO ACID = a 2-oxo acid + H<SUB>2</SUB>O<SUB>2</SUB> + NH<SUB>3</SUB> + A 2-OXO ACID
EC# 1.4.3.-O<SUB>2</SUB> + L-aspartate = H<SUB>2</SUB>O<SUB>2</SUB> + iminoaspartate
EC# 1.17.4.1Reduced Thioredoxin + UDP = Oxidized Thioredoxin + dUDP + H<SUB>2</SUB>O
EC# 1.17.4.1Reduced Thioredoxin + ADP = Oxidized Thioredoxin + dADP + H<SUB>2</SUB>O
EC# 1.17.4.-UDP + Grx = dUDP + GrxA + H<SUB>2</SUB>O
EC# 1.17.4.1Reduced Thioredoxin + CDP = Oxidized Thioredoxin + dCDP + H<SUB>2</SUB>O
EC# 1.17.4.1a 2'-deoxyribonucleoside diphosphate + Oxidized Thioredoxin + H<SUB>2</SUB>O + 2'-deoxyribonucleoside diphosphate = a ribonucleoside diphosphate + Reduced Thioredoxin + ribonucleoside diphosphate
EC# 1.17.4.1Reduced Thioredoxin + GDP = Oxidized Thioredoxin + dGDP + H<SUB>2</SUB>O
EC# 1.3.99.1fumarate + FADH<SUB>2</SUB> = succinate + FAD
EC# 1.3.99.3acyl-CoA + FAD = FADH<SUB>2</SUB> + &Delta;<SUP>2</SUP>-enoyl-CoA
EC# 1.3.99.1fumarate + reduced acceptor = succinate + acceptor
EC# 1.3.99.7glutaconyl-CoA + acceptor = reduced acceptor + CO<SUB>2</SUB> + crotonyl-CoA
EC# 1.3.99.12isobutyryl-CoA + FAD = methacrylyl-CoA + FADH<SUB>2</SUB>
EC# 1.3.99.10ETF oxidized + isovaleryl-CoA = ETF reduced + 3-methylcrotonyl-CoA
EC# 1.3.99.10isovaleryl-CoA + FAD = 3-methylcrotonyl-CoA + FADH<SUB>2</SUB>
EC# 1.3.1.10NADPH + H<SUP>+</SUP> + trans-&Delta;<SUP>2</SUP>-enoyl-acyl-ACP = acyl-ACP + NADP
EC# 1.3.1.54NADPH + precorrin-6x = NADP + precorrin-6y
EC# 1.3.1.9NADH + H<SUP>+</SUP> + trans-&Delta;<SUP>2</SUP>-enoyl-acyl-ACP = acyl-ACP + NAD
EC# 1.3.1.34trans-&Delta;<SUP>2</SUP>-decenoyl-CoA + NADP = trans-&Delta;<SUP>2</SUP>, cis-&Delta;<SUP>4</SUP>-decadienoyl-CoA + NADPH + H<SUP>+</SUP>
EC# 1.3.1.262,3-dihydrodipicolinate + NADPH + H<SUP>+</SUP> = NADP + tetrahydrodipicolinate
EC# 1.3.5.1ubiquinone(50) + succinate = Ubiquinols + ubiquinol(50) + fumarate
EC# 1.3.3.4O<SUB>2</SUB> + protoporphyrinogen = 2 H<SUB>2</SUB>O + protoporphyrin IX
EC# 1.3.3.3O<SUB>2</SUB> + coproporphyrinogen III = 2 H<SUB>2</SUB>O + 2 CO<SUB>2</SUB> + protoporphyrinogen
EC# 1.3.3.1O<SUB>2</SUB> + dihydroorotate = H<SUB>2</SUB>O<SUB>2</SUB> + orotate
EC# 1.18.99.1H<SUP>+</SUP> + FdxA = H<SUB>2</SUB> + oxidized ferredoxin
EC# 1.18.1.1NAD + REDUCED RUBREDOXIN = NADH + OXIDIZED RUBREDOXIN
EC# 1.18.1.2reduced flavodoxin + NADP = oxidized flavodoxin + NADPH
EC# 1.2.99.2reduced acceptor + CO<SUB>2</SUB> = acceptor + H<SUB>2</SUB>O + carbon monoxide
EC# 1.2.1.16succinate semialdehyde + NADP + H<SUB>2</SUB>O = NADPH + succinate
EC# 1.2.1.13phosphate + NADP + glyceraldehyde-3-phosphate = NADPH + 3-phospho-D-glyceroyl-phosphate
EC# 1.2.1.24H<SUB>2</SUB>O + NAD + succinate semialdehyde = NADH + succinate
EC# 1.2.1.27NAD + Coenzyme A + methylmalonate-semialdehyde = NADH + CO<SUB>2</SUB> + propionyl-CoA
EC# 1.2.1.-N<SUP>2</SUP>-succinylglutamic-semialdehyde + NAD = N<SUP>2</SUP>-succinylglutamate + NADH + H<SUP>+</SUP>
EC# 1.2.1.32H<SUB>2</SUB>O + NAD + 2-aminomuconate semialdehyde = NADH + 2-amino-muconate
EC# 1.2.1.31-Octanal + NAD + H<SUB>2</SUB>O = octanoate + NADH + 2 H<SUP>+</SUP>
EC# 1.2.1.54H<SUB>2</SUB>O + NAD + 4-Guanidinobutanal = NADH + 4-Guanidinobutanoate
EC# 1.2.1.38N-acetylglutamyl-phosphate + NADPH + H<SUP>+</SUP> = N-acetylglutamate semialdehyde + NADP + phosphate
EC# 1.2.1.10NADH + acetyl-CoA = NAD + Coenzyme A + acetaldehyde
EC# 1.2.1.74-hydroxybenzaldehyde + NADP + H<SUB>2</SUB>O = p-hydroxybenzoate + NADPH
EC# 1.2.1.194-amino-butyraldehyde + NAD + H<SUB>2</SUB>O = 4-aminobutyrate + NADH
EC# 1.2.1.284-hydroxybenzaldehyde + NAD + H<SUB>2</SUB>O = p-hydroxybenzoate + NADH + H<SUP>+</SUP>
EC# 1.2.1.11NADPH + L-aspartyl-4-P = NADP + phosphate + L-aspartate-semialdehyde
EC# 1.2.1.41L-glutamate-5-phosphate + NADPH + H<SUP>+</SUP> = L-glutamate &gamma;-semialdehyde + phosphate + NADP
EC# 1.2.1.8betaine aldehyde + NAD + H<SUB>2</SUB>O = betaine + NADH
EC# 1.2.1.12glyceraldehyde-3-phosphate + phosphate + NAD = 3-phospho-D-glyceroyl-phosphate + NADH + H<SUP>+</SUP>
EC# 1.2.1.452-Hydroxy-5-carboxymethylmuconate semialdehyde + NAD + H<SUB>2</SUB>O = 5-Carboxymethyl-2-hydroxymuconate + NADH
EC# 1.2.1.2NAD + formate = NADH + H<SUP>+</SUP> + CO<SUB>2</SUB>
ERYTH4PDEHYDROG-RXNerythrose-4-phosphate + NAD = erythronate-4-phosphate + NADH
EC# 1.2.1.43NADPH + CO<SUB>2</SUB> = NADP + formate
EC# 1.2.1.46H<SUB>2</SUB>O + NAD + formaldehyde = NADH + formate
EC# 1.2.7.1FdxA + CO<SUB>2</SUB> + acetyl-CoA = oxidized ferredoxin + Coenzyme A + pyruvate
EC# 1.2.7.3FdxA + CO<SUB>2</SUB> + succinyl-CoA = oxidized ferredoxin + Coenzyme A + 2-oxoglutarate
EC# 1.2.2.2pyruvate + ferricytochrome-b1 + H<SUB>2</SUB>O = acetate + CO<SUB>2</SUB> + ferrocytochrome-b1
EC# 1.2.4.1pyruvate + lipoamide = S-acetyldihydrolipoamide + CO<SUB>2</SUB>
EC# 1.2.4.4LIPOYL-BRANCHED-KETOACID-E2 + 2-keto-isovalerate = CO<SUB>2</SUB> + 2-METHYL-PROPANOYL-DIHYDROLIPOYL-E2
EC# 1.2.4.42-keto-4-methyl-pentanoate + LIPOYL-BRANCHED-KETOACID-E2 = 3-METHYL-BUTANOYL-DIHYDROLIPOYL-E2 + CO<SUB>2</SUB>
EC# 1.2.4.2DIHYDROLIPOYL-OXO-GLUT-E2 + 2-oxoglutarate = succinyl-lipoate + CO<SUB>2</SUB>
EC# 6.5.1.4a 3'-phosphate-terminated RNA + RNA 3'-TERMINAL-PHOSPHATE + ATP = a 2',3'-cyclic-phosphate-terminated RNA + RNA TERMINAL-2',3'-CYCLIC-PHOSPHATE + pyrophosphate + AMP
EC# 6.5.1.2(DEOXYRIBONUCLEOTIDE)(M) + (DEOXYRIBONUCLEOTIDE)(N) + NAD = (DEOXYRIBONUCLEOTIDE)(N+M) + nicotinamide nucleotide + AMP
EC# 6.1.1.17tRNA<SUP>glt</SUP> + L-glutamate + ATP = L-glutamyl-tRNA<SUP>glt</SUP> + pyrophosphate + AMP
EC# 6.4.1.1HCO<SUB>3</SUB><SUP>-</SUP> + pyruvate + ATP = phosphate + oxaloacetic acid + ADP
EC# 6.4.1.2AccB + acetyl-CoA + ATP = malonyl-CoA + AccB + phosphate + ADP
EC# 6.4.1.3ATP + HCO<SUB>3</SUB><SUP>-</SUP> + propionyl-CoA = ADP + phosphate + D-methylmalonyl-CoA
EC# 6.4.1.2HCO<SUB>3</SUB><SUP>-</SUP> + H<SUP>+</SUP> + acetyl-CoA + ATP = malonyl-CoA + phosphate + ADP
EC# 6.4.1.4HCO<SUB>3</SUB><SUP>-</SUP> + 3-methylcrotonyl-CoA + ATP = phosphate + trans-3-methylglutaconyl-CoA + ADP
EC# 6.2.1.5succinate + Coenzyme A + ATP = succinyl-CoA + ADP + phosphate
EC# 6.2.1.14Coenzyme A + 6-Carboxyhexanoate + ATP = 6-carboxyhexanoyl-CoA + pyrophosphate + AMP
EC# 6.2.1.3octanoate + ATP + Coenzyme A = octanoyl-CoA + AMP + pyrophosphate
EC# 6.2.1.1Coenzyme A + acetate + ATP = acetyl-CoA + pyrophosphate + AMP
EC# 6.2.1.9Coenzyme A + malate + ATP = phosphate + (3S)-3-Carboxy-3-hydroxypropanoyl-CoA + ADP
EC# 6.3.5.-adenosyl-cobyrinic acid a,c-diamide + 4 L-glutamine + 4 ATP + 4 H<SUB>2</SUB>O = adenosyl-cobyric acid + 4 L-glutamate + 4 ADP + 4 phosphate
EC# 6.3.5.4H<SUB>2</SUB>O + L-glutamine + L-aspartate + ATP = L-glutamate + L-asparagine + pyrophosphate + AMP
EC# 6.3.5.-hydrogenobyrinate + 2 L-glutamine + 2 ATP + 2 H<SUB>2</SUB>O = hydrogenobyrinate a,c-diamide + 2 L-glutamate + 2 ADP + 2 phosphate
EC# 6.3.5.5H<SUB>2</SUB>O + HCO<SUB>3</SUB><SUP>-</SUP> + L-glutamine + 2 ATP + H<SUP>+</SUP> = carbamoyl-phosphate + L-glutamate + phosphate + 2 ADP
EC# 6.3.5.1ATP + deamido-NAD + L-glutamine + H<SUB>2</SUB>O = AMP + pyrophosphate + NAD + L-glutamate
EC# 6.3.5.3ATP + 5'-phosphoribosyl-N-formylglycineamide + L-glutamine + H<SUB>2</SUB>O = ADP + phosphate + 5-phosphoribosyl-n-formylglycineamidine + L-glutamate
EC# 6.3.5.2xanthosine-5-phosphate + H<SUB>2</SUB>O + L-glutamine + ATP = L-glutamate + GMP + pyrophosphate + AMP
EC# 6.3.1.5ATP + deamido-NAD + NH<SUB>3</SUB> = AMP + pyrophosphate + NAD
EC# 6.3.1.1NH<SUB>3</SUB> + L-aspartate + ATP = L-asparagine + pyrophosphate + AMP
EC# 6.3.1.2NH<SUB>3</SUB> + L-glutamate + ATP = L-glutamine + ADP + phosphate
EC# 6.3.4.1xanthosine-5-phosphate + ATP + NH<SUB>3</SUB> = AMP + pyrophosphate + GMP
EC# 6.3.4.4L-aspartate + IMP + GTP = adenylo-succinate + phosphate + GDP
EC# 6.3.4.13ATP + 5-phosphoribosylamine + L-glycine = ADP + phosphate + 5-phospho-ribosyl-glycineamide
EC# 6.3.4.5L-aspartate + citrulline + ATP = L-arginino-succinate + pyrophosphate + AMP
EC# 6.3.4.3ATP + formate + THF = ADP + phosphate + 10-formyl-THF
EC# 6.3.4.14AccB + CO<SUB>2</SUB> + ATP = phosphate + ADP + AccB
EC# 6.3.4.2L-glutamine + H<SUB>2</SUB>O + UTP + ATP = CTP + phosphate + ADP + L-glutamate
EC# 6.3.2.13UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + meso-diaminopimelate + ATP = UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate + phosphate + ADP
EC# 6.3.2.4D-alanine + D-alanine + ATP = D-alanyl-D-alanine + phosphate + ADP
EC# 6.3.2.15D-alanyl-D-alanine + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate + ATP = UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate- D-alanyl-D-alanine + phosphate + ADP
EC# 6.3.2.12L-glutamate + 7,8-dihydropteroate + ATP = 7,8-dihydrofolate + phosphate + ADP
EC# 6.3.2.9UDP-N-acetylmuramoyl-L-alanine + D-glutamate + ATP = UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + phosphate + ADP
EC# 6.3.2.17L-glutamate + H4PteGlu(n+1) + ATP = H4PteGlu(n) + phosphate + ADP
EC# 6.3.2.8L-alanine + UDP-N-acetylmuramate + ATP = UDP-N-acetylmuramoyl-L-alanine + phosphate + ADP
EC# 6.3.2.3L-glycine + L-&gamma;-glutamylcysteine + ATP = reduced glutathione + phosphate + ADP
EC# 6.3.2.6ATP + phosphoribosyl-carboxy-aminoimidazole + L-aspartate = ADP + phosphate + 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole
EC# 6.3.2.2L-cysteine + L-glutamate + ATP = L-&gamma;-glutamylcysteine + phosphate + ADP
EC# 6.3.2.1&beta;-alanine + L-pantoate + ATP = pantothenate + pyrophosphate + AMP
EC# 6.3.2.54'-phosphopantothenate + L-cysteine + CTP = pyrophosphate + CMP + 4'-phospho-N-pantothenoylcysteine
EC# 6.3.3.3CO<SUB>2</SUB> + 7,8-diaminononanoate + ATP = dethiobiotin + phosphate + ADP
EC# 6.3.3.1ATP + 5-phosphoribosyl-n-formylglycineamidine = ADP + phosphate + 5'-phosphoribosyl-5-aminoimidazole
EC# 2.-.-.-(KDO)-lipid IV(A) + CMP-3-deoxy-D-<i>manno</i>-octulosonate = KDO<SUB>2</SUB>-lipid IV<SUB>A</SUB> + CMP
EC# 2.-.-.-CMP-3-deoxy-D-<i>manno</i>-octulosonate + lipid IV(A) = (KDO)-lipid IV(A) + CMP
EC# 2.2.1.2glyceraldehyde-3-phosphate + sedoheptulose-7-phosphate = fructose-6-phosphate + erythrose-4-phosphate
EC# 2.2.1.1ribose-5-phosphate + xylulose-5-phosphate = sedoheptulose-7-phosphate + glyceraldehyde-3-phosphate
EC# 2.2.1.1fructose-6-phosphate + glyceraldehyde-3-phosphate = xylulose-5-phosphate + erythrose-4-phosphate
EC# 2.3.2.2AN AMINO ACID + (5-L-GLUTAMYL)-PEPTIDE = a peptide + 5-L-GLUTAMYL-AMINO ACID + PEPTIDE
EC# 2.3.1.129(R)-3-hydroxymyristoyl-ACP + UDP-N-acetyl-D-glucosamine = UDP-3-O-(3-hydroxymyristoyl)-N-acetylglucosamine + [acyl carrier protein]
EC# 2.3.1.511-acyl-sn-glycerol-3P + acyl-ACP = L-phosphatidate + [acyl carrier protein]
EC# 2.3.1.-UDP-3-O-(3-hydroxymyristoyl)glucosamine + (R)-3-hydroxymyristoyl-ACP = UDP-2,3-bis(3-hydroxymyristoyl)glucosamine + [acyl carrier protein]
EC# 2.3.1.118an N-hydroxyarylamine + AN N-HYDROXYARYLAMINE + acetyl-CoA = an N-acetoxyarylamine + AN N-ACETOXYARYLAMINE + Coenzyme A
EC# 2.3.1.117H<SUB>2</SUB>O + tetrahydrodipicolinate + succinyl-CoA = N-succinyl-2-amino-6-ketopimelate + Coenzyme A
EC# 2.3.1.41acetyl-ACP + malonyl-ACP = [acyl carrier protein] + acetoacetyl-ACP + CO<SUB>2</SUB>
EC# 2.3.1.30L-serine + acetyl-CoA = O-acetyl-L-serine + Coenzyme A
EC# 2.3.1.41acyl-ACP + malonyl-ACP = [acyl carrier protein] + &beta;-ketoacyl-ACP + CO<SUB>2</SUB>
EC# 2.3.1.54pyruvate + Coenzyme A = formate + acetyl-CoA
EC# 2.3.1.47L-alanine + 6-carboxyhexanoyl-CoA = CO<SUB>2</SUB> + Coenzyme A + 8-amino-7-oxononanoate
EC# 2.3.1.-propionyl-CoA + phosphate = propionyl-P + Coenzyme A
EC# 2.3.1.9acetoacetyl-CoA + Coenzyme A = 2 acetyl-CoA
EC# 2.3.1.8phosphate + acetyl-CoA = acetylphosphate + Coenzyme A
EC# 2.3.1.38[acyl carrier protein] + acetyl-CoA = acetyl-ACP + Coenzyme A
EC# 2.3.1.-KDO<SUB>2</SUB>-lipid IV<SUB>A</SUB> + palmitoleoyl-ACP = KDO<SUB>2</SUB>-(palmitoleoyl)-lipid IV&